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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
6.67
Human Site:
S400
Identified Species:
11.28
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
S400
Q
Y
I
E
S
S
D
S
E
E
I
E
T
S
E
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
S400
Q
Y
I
E
S
S
D
S
E
E
I
E
T
S
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
D497
V
Q
Y
N
E
S
S
D
S
E
E
N
E
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
S394
I
S
V
Q
Y
I
E
S
S
D
S
E
E
I
E
Rat
Rattus norvegicus
NP_001099948
974
110023
D365
S
E
E
P
S
I
S
D
V
S
E
K
S
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
L355
A
E
R
P
R
A
T
L
I
I
C
P
L
S
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
Q390
S
S
S
R
P
K
R
Q
K
A
S
K
A
K
Y
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
V380
A
V
V
L
L
D
D
V
E
F
A
A
A
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
A448
N
H
Q
K
H
A
L
A
W
M
S
W
R
E
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
A476
P
G
P
S
Q
P
V
A
L
L
P
G
P
R
P
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
A270
G
G
N
K
D
N
V
A
E
E
I
G
G
D
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
G352
L
K
T
D
D
V
V
G
M
N
V
S
Q
K
T
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
I261
K
G
Q
L
K
I
Y
I
Y
H
G
A
S
R
T
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
P558
Q
P
C
F
Y
V
N
P
Y
S
G
D
L
S
L
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
13.3
N.A.
20
6.6
N.A.
6.6
N.A.
0
20
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
20
N.A.
46.6
26.6
N.A.
13.3
N.A.
13.3
26.6
N.A.
26.6
N.A.
N.A.
6.6
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
20
N.A.
N.A.
0
0
13.3
P-Site Similarity:
46.6
N.A.
N.A.
13.3
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
15
0
22
0
8
8
15
15
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
8
15
8
22
15
0
8
0
8
0
8
8
% D
% Glu:
0
15
8
15
8
0
8
0
29
29
15
22
15
8
29
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
22
0
0
0
0
0
8
0
0
15
15
8
0
0
% G
% His:
0
8
0
0
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
15
0
0
22
0
8
8
8
22
0
0
8
0
% I
% Lys:
8
8
0
15
8
8
0
0
8
0
0
15
0
15
0
% K
% Leu:
8
0
0
15
8
0
8
8
8
8
0
0
15
8
8
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
8
0
8
8
0
8
8
0
0
8
0
8
0
8
0
% N
% Pro:
8
8
8
15
8
8
0
8
0
0
8
8
8
0
8
% P
% Gln:
22
8
15
8
8
0
0
8
0
0
0
0
8
0
0
% Q
% Arg:
0
0
8
8
8
0
8
0
0
0
0
0
8
15
8
% R
% Ser:
15
15
8
8
22
22
15
22
15
15
22
8
15
29
8
% S
% Thr:
0
0
8
0
0
0
8
0
0
0
0
0
15
8
15
% T
% Val:
8
8
15
0
0
15
22
8
8
0
8
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% W
% Tyr:
0
15
8
0
15
0
8
0
15
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _